GM1 (monosialotetrahexosylganglioside) the "prototype" ganglioside, is a member of the ganglio series of gangliosides which contain one sialic acid residue.
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Jan 29, 2020 · It is a milestone that GM1 is one of the main actors in determining the neuronal functions that allows humans to have an intellectual life.
The systemic administration of monosialotetrahexosylganglioside (GM1 or Sygen) has been neuroprotective in a variety of models of experimental CNS injury. Like ...
Apr 26, 2023 · GM1 gangliosidosis is an inherited disorder that destroys nerve cells (neurons) in the brain and spinal cord.
GM1 gangliosidosis (GM1) is caused by mutations in the gene that encodes lysosomal β-galactosidase (GLB1), and similar to other LSDs, is characterized by severe ...
May 31, 2023 · GM1 (or GM1a) is a glycosphingolipid (GSL) consisting of a pentasaccharide and a ceramide (Cer), which are coupled together by a β-glycosidic ...
GM1 gangliosidosis, also called beta-galactosidase-1 deficiency, is a genetic disorder that progressively destroys nerve cells in the brain and spinal cord.
GM1 gangliosidosis is a progressive, neurosomatic, lysosomal storage disorder caused by mutations in the GLB1 gene encoding the enzyme β-galactosidase.
Common gangliosides ; One NANA ("M"). GM1 · GM2 · GM3 ; Two NANAs ("D"). GD1a · GD1b · GD2 · GD3 ; Three NANAs ("T"). GT1b · GT3.
Apr 24, 2018 · GM1 ganglioside and its derivative asialo-GM1 ganglioside (GA1), glycoprotein-derived oligosaccharides, and keratan sulfate are found at ...
