Phenylalkylamines such as verapamil, gallopamil, or devapamil block the L-type calcium current in an use-dependent manner from the intracellular side of the membrane. In contrast to PAAs, benzothiazepines access the channel from the extracellular side.
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Phenylalkylamine Derivatives ; Verapamil, A non-dihydropyridine calcium channel blocker used in the treatment of angina, arrhythmia, and hypertension. ; Bepridil ...
They can be classified into three groups: the phenylalkylamines, the benzothiazepines and the dihydropyridines. The phenylalkylamines include verapamil.
This class of drugs, which specifically block the entry of calcium into cells,89 has been used in the treatment of angina, hypertension, and other ...
Phenylalkylamine derivatives produce several types of behavioral effects including central stimulation and hallucinogenic activity.
Calcium channel blockers are used as antihypertensive drugs, ie, as medications to decrease blood pressure in patients with hypertension.
The following have been classified under this therapeutic category. bepridil · verapamil. Synonyms. None. The information on this website is not intended ...
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The majority of calcium antagonists used clinically belong to three distinct chemical classes: the phenylalkylamines, the dihydropyridines, and the ...
Jul 1, 1995 · We conclude that felodipine and verapamil have qualitatively different, time-dependent actions on efferent sympathetic nervous system activity.
Jun 13, 2005 · Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina, 19 and was ...
