H1-blockers can be classified as first-generation agents (Table 1) that are known to have sedating properties due to penetration of the blood–brain barrier and as nonsedating second-generation agents (Tables 2 and 3) that are more selective for peripheral histamine receptors.
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Classes · Diphenhydramine · Carbinoxamine · Doxylamine · Orphenadrine · Bromazine · Clemastine · Dimenhydrinate.
Traditionally, H1 antihistamines have been classified into 6 chemical groups: alkylamines, ethanolamines, ethylenediamines, phenothiazines, piperazines, and ...
Histamine H1 Antagonists ; Ketotifen, A histamine H1 receptor blocker and mast cell stabilizer used to treat mild atopic asthma and allergic conjunctivitis.
H1-blockers can be classified as first-generation agents (Table 1) that are known to have sedating properties due to penetration of the blood–brain barrier ...
Sep 18, 2023 · Commonly used H1 antagonists currently available in the United States are cetirizine, levocetirizine, desloratadine, loratadine, and fexofenadine.
Two H1-antagonists, astemizole and terfenadine, have been found to prolong the QTc interval and, rarely, to cause cardiac dysrhythmias after overdose.
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Histamine H1 Antagonists, Non-Sedating ; Cetirizine, A selective Histamine-1 antagonist drug used in allergic rhinitis and chronic urticaria. ; Loratadine, A ...
Sep 4, 2012 · Classes · Diphenhydramine · Carbinoxamine · Doxylamine · Clemastine · Dimenhydrinate.
