However, it was withdrawn from the market because of its hepatotoxicity. The medical use of iproniazid was discontinued in most of the world in the 1960s, but remained in use in France until its discontinuation in 2015.
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Iproniazid has been withdrawn from market in several countries, including the United States, but is still used in many countries [6,45].
Iproniazid has been replaced in antidepressant therapy by other members of the monoamine-oxidase inhibitor series (e.g., isocarboxazid, phenelzine, and ...
Jun 1, 2021 · Use of INH and iproniazid as antidepressants ended in 1961: hepatotoxicity in doses used in depressed patients halted treatment programs and ...
While it has historic significance in the treatment of depression, its use has largely been discontinued due to the emergence of newer medications with better ...
While iproniazid was marketed as an antitubercular compound under the trade name Marsilid® in 1958, it was used off-label to treat patients suffering from MDD.
Unfortunately, iproniazid had to be withdrawn from the market in 1961 because of what was considered an unacceptable incidence of hepatitis (Kline 1970; Kline ...
In the mid-1950s, Iproniazid was approved as one of the antidepressant drugs. This drug, however, has been discontinued because of the damage it may cause to a ...
By 1957 the ataractics or tranquilizers were widely used in the treatment of many mental diseases, including schizophrenia and the neuroses.
It is the first drug of the monamine-oxidase inhibitor series. It was used widely as antidepressants until the iproniazid side effects came out to be liver ...
