Iproniazid was originally developed for the treatment of tuberculosis, but in 1952, its antidepressant properties were discovered when researchers noted that patients became inappropriately happy when given isoniazid, a structural analog of iproniazid.
People also ask
What type of drug is iproniazid?
How does iproniazid work?
Is iproniazid an example of a tranquilizer?
Is iproniazid known as the first modern antidepressant?
Iproniazid is a drug that was initially investigated as an anti-tuberculosis medication but later found to have a mood-elevating effect.
Jun 1, 2021 · With the advent of isoniazid chemotherapy, transformation of tuberculosis patients from morbidly depressive to euphoric was noted. Isoniazid was ...
In 1954, trials of iproniazid for tuberculosis showed that the mood of some subjects improved during treatment. Iproniazid was found to inhibit monoamine ...
The duration of iproniazid treatment for the entire group ranged from 11 days to five and one-half months; only five received the drug longer than four months.
The initial studies of the hydrazides in tuberculosis concerned chiefly the isopropyl derivative of isonicotinic acid or iproniazid; the parent com-.
Sep 17, 2001 · There were various accounts of euphoria among patients receiving iproniazid after its introduction as a TB drug in 1952. Zeller et al.
Feb 27, 2021 · His experiments confirmed the euphoric effect of iproniazid first reported in the treatment of tuberculosis. They were undertaken by Dr. Kline ...
1. Iproniazid has a great effect in the control of bone and joint infection by the Mycobacterium tuberculosis. 2. For the present we believe iproniazid to ...
Iproniazid had been synthesized by Fox in 1951 2 as part of a deliberate search for new antituberculosis drugs.
