Isoniazid and its derivative iproniazid were introduced in 1951 as pharmacologic treatments for tuberculosis. It was found that iproniazid inhibited the enzyme MAO and that patients with tuberculosis who were treated with this drug experienced an elevation of mood.
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Acetylhydrazine, a metabolite of isoniazid, a widely used antituberculosis drug, and isopropylhydrazine, a metabolite of iproniazid, an antidepressant ...
Acetylhydrazine, a metabolite of isoniazid, a widely used antituberculosis drug, and isopropylhydrazine, a metabolite of iproniazid, an antidepressant ...
Iproniazid can also be metabolised by O-dealkylation from iproniazid to acetone and isoniazid. Isoniazid can undergo further metabolism via multiple ...
The clinical effect of isoniazid and iproniazid in the treatment of pulmonary tuberculosis.
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Prior to its introduction as an antidepressant, iproniazid was studied as a drug similar in function to the antituberculotic drug isoniazid, which it resembles ...
CONTROLLED STUDY OF ISONIAZID AND IPRONIAZID. 575 improvement. Ten per cent of 33 who finished one year of isoniazid fell in the same category. Project B: At ...
To the Editor:— Isoniazid (isonicotinic acid hydrazide) and iproniazid (1-isonicotinyl-2-isopropylhydrazine) are being given to many patients with ...
Only 10 of the 44 patients who received isoniazid had significant relief of joint manifestations after six months, and 20 of the remaining 34 were given ...
