Elevated PAPP-A levels have been identified as a significant factor associated with an increased risk of placenta accreta and its associated complications, including massive peripartum hemorrhage and the need for hysterectomy.
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Elevated PAPP-A values in the first trimester of pregnancy may be a useful marker for identifying women at higher risk of PAS and adverse outcomes.
Jul 3, 2020 · Both low and high PAPP-A concentrations in the first trimester of pregnancy are associated with increased risk of delivery before 32 weeks in twin gestation.
Higher PAPP-A Values in Pregnant Women Complicated with ...
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Mar 14, 2023 · PAPP-A levels in the patients who developed PE were remarkably higher than those in most of works reported before, and this could have clinical ...
Extreme values of the first-trimester biochemical analyte PAPP-A are associated with higher rates of adverse perinatal outcomes, such as IUGR and IUFD.
Mar 20, 2020 · Conversely, a high PAPP-A appears to be associated with a statistically significantly lower prevalence of SGA and with an increased risk of LGAs ...
Higher PAPP-A levels suggest the benign course of pregnancy. It can be an early manifestation of the healthy foetus in the absence of genetic abnormality.
PAPP-A2 concentrations and MoM values were higher in women with subsequent PE as compared to controls at 26–28 weeks. Higher PAPP-A2 MoM values were ...
Dec 11, 2023 · Lower maternal PAPP-A in early pregnancy can lead to glucose intolerance and increase the risk of subsequent GDM development.
Feb 5, 2023 · Pregnant women with hypothyroidism have higher median values of the plasma concentrations of PAPP-A and the free subunit of β-hCG than pregnant ...
