Did you mean: ganglioside
A ganglioside is a molecule composed of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acids linked on the sugar chain.
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What is the function of ganglioside?
Gangliosides are enriched in cell membrane microdomains (“lipid rafts”) and play important roles in the modulation of membrane proteins and ion channels, in cell signaling and in the communication among cells.
What are the symptoms of Gangliosidosis?
Signs and symptoms children with GM1 gangliosidosis may experience include:
Distinct facial features (coarse facial features)
Poor muscle tone (hypotonia)
Enlargement of the liver and spleen (hepatosplenomegaly)
Exaggerated startle reaction.
Developmental regression.
Skeletal abnormalities.
Seizures.
Visual impairment.
What is the prognosis for gangliosidosis?
Outlook / Prognosis
The life expectancy and quality of life for someone with GM1 gangliosidosis varies depending on the type: Babies with type 1 (classic infantile) may live to age 2. Children with type 2 (juvenile) may live into mid-childhood or early adulthood depending on their age at the onset of symptoms.
What does ganglioside test for?
May be useful when assessing for primarily motor neuron disease and motor neuropathies. Test by itself is not diagnostic and should be used in conjunction with other clinical parameters to confirm disease.
Gangliosides are highly purified sialic acid-containing glycolipids that are useful as markers of various cell types and antigens. View ...
In organic chemistry, GM2 is a type of ganglioside. G refers to ganglioside, the M is for monosialic and 2 refers to the fact that it was the second ...
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The DotDiver Gangliosid IgG is an immunodot assay for the qualitative determination of IgG autoantibodies to gangliosides in human serum or plasma.
Gangliosides are highly purified sialic acid-containing glycolipids that are useful as markers of various cell types and antigens. View ...
The Anti-Gangliosid Dot is intended as an aid in the diagnosis of peripheral neurological disorders in conjunction with other clinical and laboratory findings.
Anti-ganglioside antibodies are principally associated with autoimmune peripheral neuropathies. In these disorders, immune attack is inadvertently directed ...
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The DotDiver Gangliosid IgM is an immunodot assay for the qualitative determination of IgM autoantibodies to gangliosides in human serum or plasma.
Ganglioside sind eine vor allem im Nervensystem vorkommende Substanzklasse, die zu den Sphingolipiden zählt.
Gangliosides, glycosphingolipids present in the membranes of neuronal and other cells, are natural receptors for a number of bacterial toxins and viruses ...
