Did you mean: ganglioside
A ganglioside is a molecule composed of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acids linked on the sugar chain.
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What is the function of a ganglioside?
Gangliosides are enriched in cell membrane microdomains (“lipid rafts”) and play important roles in the modulation of membrane proteins and ion channels, in cell signaling and in the communication among cells.
What is the cause of gangliosidosis?
GM1 gangliosidosis is caused by genetic mutations, also known as pathogenic variants. Genetic mutations can be hereditary, when parents pass them down to their children, or they may occur randomly when cells are dividing.
What is the disease gangliosides?
The gangliosidoses comprise a family of autosomal recessive lysosomal storage diseases characterized by the accumulation of complex glycolipids in the brain and other tissues, associated with a range of progressive neurologic phenotypes.
Are gangliosides good or bad?
Gangliosides are believed to play a role in neuroplasticity through influences on neurogenesis, synaptic plasticity, neurotransmission and axonal growth. Furthermore, they also mediate neuronal differentiation, maintenance and repair [4].
Find gangliosid and related products for scientific research at MilliporeSigma.
In organic chemistry, GM2 is a type of ganglioside. G refers to ganglioside, the M is for monosialic and 2 refers to the fact that it was the second ...
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The DotDiver Gangliosid IgG is an immunodot assay for the qualitative determination of IgG autoantibodies to gangliosides in human serum or plasma.
Ganglioside GM1 Contributes to the State of Insulin Resistance in Senescent Human Arterial Endothelial Cells. Norihiko Sasaki et al. The ...
Gangliosides, glycosphingolipids present in the membranes of neuronal and other cells, are natural receptors for a number of bacterial toxins and viruses ...
The Anti-Gangliosid Dot is intended as an aid in the diagnosis of peripheral neurological disorders in conjunction with other clinical and laboratory findings.
Jan 21, 2022 · We have endeavored in this review to summarize our findings, which point to a systemic deficiency of ganglioside GM1 in Parkinson's disease (PD) tissues.
Aug 1, 2021 · Gangliosides are complex sphingolipids and components of the cell membrane in the central and peripheral nervous system that help determine ...
