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Rare connective tissue diseases more common in HAE, study finds

Angioedema News
Rare connective tissue diseases are more common among hereditary angioedema (HAE) patients than in the general population, a study found.
2 weeks ago

Link between COVID-19 and long-term risk of autoimmune and autoinflammatory connective tissue disorders

News-Medical
The severity of COVID-19 was found to influence autoimmune risks, with patients in intensive care having markedly higher risks for sarcoidosis, Sjögren syndrome...
1 month ago

Association of cumulative methylprednisolone dosages with mortality risk from pneumonia in connective tissue disease patients | Scientific Reports

Nature
Corticosteroid is essential in the treatment regimen for connective tissue disease (CTD); however, its long-term use poses significant risks,...
1 month ago

Immunological characteristics of bronchoalveolar lavage fluid and blood across connective tissue disease-associated interstitial lung diseases

Frontiers
Interstitial lung disease (ILD) is a serious complication of connective tissue diseases (CTDs). The heterogeneity of ILDs reflects differences in...
1 month ago

Rare connective tissue diseases in patients with C1-inhibitor deficiency hereditary angioedema: first evidence on prevalence and distribution from a large Italian cohort study

Frontiers
We aim at evaluating for the first time prevalence and distribution of RCTDs -Systemic Lupus Erytematosus (SLE), primary Sjogren Syndrome (SjS), primary...
1 month ago

Biallelic and monoallelic variants in EFEMP1 can cause a severe and distinct subtype of heritable connective tissue disorder | European Journal of Human Genetics

Nature
Variants in EFEMP1, encoding Fibulin-3, were previously reported as a rare cause of heritable connective tissue disorder (HCTD) with recurrent hernias and...
2 months ago

The role of immune cells in the pathogenesis of connective tissue diseases-associated pulmonary arterial hypertension

Frontiers
This review explores the potential mechanisms by which immune cells contribute to the development of CTD-PAH and examines the clinical application of...
2 months ago

Interstitial (Nonidiopathic) Pulmonary Fibrosis: Practice Essentials, Pathophysiology, Etiology

Medscape
Diffuse parenchymal lung diseases (DPLDs) comprise a heterogenous group of disorders. Clinical, physiologic, radiographic, and pathologic presentations of...
3 months ago

Sex Dimorphism in Pulmonary Arterial Hypertension Associated With Autoimmune Diseases

American Heart Association Journals
Pulmonary hypertension is a rare, incurable, and progressive disease. Although there is increasing evidence that immune disorders, particularly those...
3 months ago

Genetic testing and human leukocyte antigen in patients with hypertrophic cardiomyopathy and connective tissue diseases

Frontiers
This study aims to address this gap in the literature by investigating the role of HLA and performing genetic testing in patients with HCM and connective...
4 months ago