Auer rods (or Auer bodies) are large, crystalline cytoplasmic inclusion bodies sometimes observed in myeloid blast cells during acute myeloid leukemia, ...
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What is an Auer body?
(ow′ĕr) [John Auer, U.S. physician, 1875-1948] Rod-shaped structures, present in the cytoplasm of myeloblasts, myelocytes, and monoblasts, found in leukemia. Also called Auer rods.
What do Auer rods indicate?
Auer rods are red needlelike crystals that contain peroxidase (arrows) and are an occasional but highly specific finding for a myeloid neoplastic disorder. Ringed sideroblasts are red blood cell precursors that contain cytoplasmic iron that stains blue with a Prussian-blue stain.
What are Auer rods in peripheral blood?
Auer rods are not found in mature/physiological granulocytes. However, in bone marrow, Auer rods in maturing granulopoiesis are typical for core-binding-factor AML, like AML with inv(16), and for acute promyelocytic leukemia (APL) with translocation t(15;17).
What are Auer rods in myeloma?
Some of them had Auer rod-like needle-shaped crystalline intracytoplasmic inclusions. A few of them were arranged in bundles, thus mimicking faggot cells. These inclusions were myeloperoxidase (MPO) and Sudan black B (SBB) negative. Skeletal survey revealed multiple diffuse bony lytic lesions.
Auer rods are pink or red-stained needle-shaped structures seen in the cytoplasm of myeloid cells, containing agglomeration of azurophilic granules ...
Dec 27, 2022 · Auer bodies were first described by light microscopy as stick-like and spiculate bodies in the cytoplasm of leukemic cells by John Auer in 1906.
To the Editor:—Auer bodies are rod-shaped inclusions formed from azurophilic granules.1 These structures have long been recognized in the blast cells of.
Auer rods are red staining, needle-like bodies seen in the cytoplasm of myeloblasts, and/or progranulocytes in certain leukemias. Auer rods (see arrow in ...
As far back as 1924 Nakashima theorized that Auer bodies might be related to azurophilic granulesseen in both the myelocytic and monocytic cells, and proposed ...
With the aid of the electron microscope, Auer bodies have been found to be coacervates of laminated, homogeneous, crystalline plaques with the long axis of the ...
Sep 19, 2020 · The Auer body is the hallmark of myeloid neoplasms such as acute myeloid leukemia (AML) or myelodysplastic syndrome.
Auer rods manifest either alone or as faggot cells (containing bundles of Auer ... Auer rods) in various ... Inclusion Bodies / ultrastructure; Leukemia ...
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Since the discovery by Auer,1 in 1906, of certain rodlike bodies in the red blood cells in a case of acute leukemia, several additional articles have.
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