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Longitudinal assessment of established risk stratification models in patients with monoclonal gammopathy of undetermined significance

Nature
Risk of progression of monoclonal gammopathy of undetermined significance (MGUS) into multiple myeloma and related plasma cell disorders can...
1 month ago

Progression of monoclonal gammopathy of undetermined significance to multiple myeloma is associated with enhanced translational quality control and overall loss of surface antigens

Journal of Translational Medicine
Progression from MGUS to MM is accompanied by upregulated EIF2 signaling, DNA repair, and proteins involved in translational quality control.
3 months ago

No association found for autoimmune disease, monoclonal gammopathy

Medical Xpress
In a systematically screened population, there is no association between autoimmune disease and monoclonal gammopathy of undetermined...
4 months ago

Case report: Schnitzler-like syndrome without monoclonal gammopathy

Frontiers
We here report a case of Schnitzler-like syndrome without gammopathy in which we describe various mutations potentially related to inflammatory processes.
8 months ago

A Case Report: Monoclonal Gammopathy of Undetermined Significance Presenting With Renal Amyloidosis and Reactive Thrombocytosis

Cureus
Monoclonal gammopathy of undetermined significance (MGUS) is a pre-neoplastic condition involving plasma cells or lymphoplasmacytic...
5 months ago

Model Predicts Need for Bone Marrow Sampling in Monoclonal Gammopathy of Undetermined Significance

HealthDay
A model can predict smoldering multiple myeloma or worse in a cohort of persons with presumed monoclonal gammopathy of undetermined...
6 months ago

Haplotype analysis identifies functional elements in monoclonal gammopathy of unknown significance

Nature
Genome-wide association studies (GWASs) based on common single nucleotide polymorphisms (SNPs) have identified several loci associated with...
1 month ago

Doubt Cast on MGUS-Autoimmune Disease Link

MedPage Today
The not-entirely-rare condition known as monoclonal gammopathy of undetermined significance (MGUS) did not appear to raise risk for autoimmune disease.
4 months ago

Cancer treatment works to control acquired angioedema in elderly man

Angioedema News
The case of an elderly man who developed acquired angioedema associated with an underlying blood disorder called monoclonal gammopathy was...
3 weeks ago

New Tools for Monitoring Multiple Myeloma

Medscape
The starting point for monitoring is the monoclonal protein secreted by the myeloma tumor cell, which can be measured in serum and urine.
3 months ago