WO1989006904A1 - Insect-repellent composition - Google Patents

Insect-repellent composition Download PDF

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Publication number
WO1989006904A1
WO1989006904A1 PCT/EP1989/000062 EP8900062W WO8906904A1 WO 1989006904 A1 WO1989006904 A1 WO 1989006904A1 EP 8900062 W EP8900062 W EP 8900062W WO 8906904 A1 WO8906904 A1 WO 8906904A1
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WO
WIPO (PCT)
Prior art keywords
agent
weight
composition according
composition
toluamide
Prior art date
Application number
PCT/EP1989/000062
Other languages
French (fr)
Inventor
Serge André LEUTHOLD
Original Assignee
Leuthold Serge Andre
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leuthold Serge Andre filed Critical Leuthold Serge Andre
Publication of WO1989006904A1 publication Critical patent/WO1989006904A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08—Magnoliopsida [dicotyledons]
    • A01N65/36—Rutaceae [Rue family], e.g. lime, orange, lemon, corktree or pricklyash
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08—Magnoliopsida [dicotyledons]
    • A01N65/12—Asteraceae or Compositae [Aster or Sunflower family], e.g. daisy, pyrethrum, artichoke, lettuce, sunflower, wormwood or tarragon
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08—Magnoliopsida [dicotyledons]
    • A01N65/22—Lamiaceae or Labiatae [Mint family], e.g. thyme, rosemary, skullcap, selfheal, lavender, perilla, pennyroyal, peppermint or spearmint
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/817—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Compositions or derivatives of such polymers, e.g. vinylimidazol, vinylcaprolactame, allylamines (Polyquaternium 6)
    • A61K8/8176—Homopolymers of N-vinyl-pyrrolidones. Compositions of derivatives of such polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/02—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings containing insect repellants

Definitions

  • the present invention relates to an insect repellant composition for application to human skin as well as hair, or clothing, as well as the fur of animals.
  • the object of the invention is to provide an insect repellent composition which makes it possible to remedy the main drawbacks presented by known repellent compositions; namely: unpleasant odor and limited duration of effectiveness either by absorption or m abolishing Li on of the composition by the skin, or by perspiration due to high heat or stress or by abrasion of the composition caused in particular by washing the treated surface or by the movement of air on this surface. This is how we observe efficiency reductions of around 60%, compared to a wind-free atmosphere, when the wind reaches a speed of 190m / minute.
  • the composition according to the invention comprises at least one active repellant, chosen from extracts of pelargonium, geranium, lavender, pyrethrum, lemon flower, as well as N, N-dié hy1-m-toluamide, a plasticizing agent and an agent amplifying the repellent effect of the above active compounds.
  • the plasticizing agent is a vinyl compound.
  • the vinyl compound is polyvinylpyrrolidone.
  • the amplifying agent is cyclopentane-1-one-2-npentane-3-methyl ethyl ester known under the name of Hedione.
  • the composition comprises, by weight, from 30 to 75% of 95% ethanol, from 5 to 50% of N, N-diethyl-m-toluamide, from 0, there 2% of polyvinylpyrrolidone, from 2 to 10% of isopropyl myristate, from 2 to 10% of dipropylene glycol, from 0.1 to 2.5% of amplifier, from 0.1 to 2.5% of a solubilizing homogenizing agent and natural extracts from 0.1 to 2.5%.
  • the composition according to the invention which is repellent for most insects and in particular for the following mosquitoes: ⁇ edes Aegypti, Culex, Mansonia, Anopheles, Psorophora, for fleas, ticks, horseflies, black flies, black flies stable, Cerotopogonidae, has the main characteristic of allowing the creation, on covered surfaces and mainly on the skin where the repellant compositions lose their effectiveness as quickly as possible due to absorption, metabolization, perspiration and / or l 'abrasion, a film, which resists time, external conditions as well as changes in the state of the covered surface and which regulates and slows its release from the active ingredients of the composition, in which most of these ingredients remain present active repellents, ingredients whose activity is advantageously increased by the incorporation into the composition of an enhancer, said composition also having the advantage of being made up mainly of natural products which are non-toxic for humans and animals .
  • This composition whose odor is pleasant and which contains, according to the invention and as described below, a plasticizing and fixing agent as well as an amplifying agent, has real repulsive activity for a minimum period of 4 to 8 hours which could reach 14 hours depending on external conditions when it is applied in the following quantities, which vary in particular according to outdoor atmospheric conditions, such as the temperature whose rise causes dispersion or abrasion from 0.05 to 0, 2 mg per cm on the skin and
  • Said composition which contains polyvinylpyrrolidone, which constitutes the plasticizing and fixing agent for the formation of the abovementioned film, natural active repellent extracts, such as pelargonium, geranium, lavender, pyrethrum, lemon flowers, as well as NN-die hy1-m-toluamide, an amplifier consisting of cyclopentane -l-one-2- npentane-3-methyl ethyl ester whose property is to ensure a synergistic effect with the active repellent extracts, advantageously comprises, by weight, from 30 to 75% of 95% ethanol, from 5 to 50% of N, N-5 diethyl-m-toluamide, from 0.4 to 2% of polyvinylpyrrolidone, from 2 to 10% of isopropyl myristate, from 2 to 10% of dipropylene glycol, from 0.1 to 2.5% of the aforementioned enhancer and from 0.1 to 2.5% of a solubilizing homogenizing
  • composition 10 polyoxyethylene nonyl phenyl ether known as "Lamacite" and from 0.1 to 2.5% of natural repellents.
  • the aforementioned composition may also comprise a dye improving its appearance, this dye, introduced into the composition at a rate of
  • composition comprising, by weight, 65.5% 95% ethanol, 20% N, N-diethyl-m-toluamide, 1% polyvinylpyrrolidone, 8% isopropyl myristate, 4% dipropylene glycol, 0.1% amplifying agent, 0.5% solubilizing homogenizing agent and 0.9%
  • the repellant composition can be either in the form of an aerosol, or in the form of a gel which can in particular be used in a dispenser with a dispensing head.
  • either propellant is used as durosol, at a rate of 20 to 25% by weight, ie a mixture of propane and butane at a rate of 40% by weight.
  • the composition When the composition is in the form of a gel, it comprises by weight, 45 to 55% of the composition defined above, 25 to 35% of demineralized water, 12.7 to 17.5% of alcohol 95% ethyl, from 0.1 to 1.3% of a viscosity-increasing agent, such as a very high molecular weight polymer known as a "carbomer”, from 1.5% to 4.5% of hydrogenated cod liver oil, known in particular under the name of "Cremophor 2H40" and from 0.5 to 2% of polyoxyethylene (15) cocoamine known under the name of "Ethomeen C / 25".
  • a viscosity-increasing agent such as a very high molecular weight polymer known as a "carbomer”
  • hydrogenated cod liver oil known in particular under the name of "Cremophor 2H40”
  • polyoxyethylene (15) cocoamine known under the name of "Ethomeen C / 25”.
  • the composition is advantageously that which is defined above, and more particularly that which comprises 65.5% of 95% ethanol, 20% of N, N-diethyl-1-m-toluamide, 1% polyvinylpyrrolidone, 8% isopropyl myristate, 4% dipropylene glycol, 0.1% amplifier, 0.5% solubilizing homogenizing agent and 0.9% natural repellents.

Abstract

An insect repellent composition contains an agent which amplifies the repellent effects of the active ingredients, and a vinyl placticizing agent. Said composition is characterized in that it contains 30 to 75 wt. % of 95 % ethanol, 5 to 50 wt. % of N,N diéthyl-m-toluamide, 0.1 to 2 wt. % of polyvinylpyrrolidone, 2 to 10 % of isopropyl myristate, 2 to 10 wt. % of dipropylene glycol, 0.1 to 2.5 wt. % of amplifying agent, 0.1 to 2.5 wt. % of a solubilizing homogenizing agent, and 0.1 to 2.5 wt. % of natural repellent extracts.

Description

COMPOSITION REPULSIVE D'INSECTES.REPELLANT COMPOSITION OF INSECTS.
La présente invention a pour objet ' une composition répulsive pour insectes destinée à être appliquée sur la peau humaine tout aussi bien que sur les cheveux, ou vêtement, ainsi que sur le pelage des animaux .The present invention relates to an insect repellant composition for application to human skin as well as hair, or clothing, as well as the fur of animals.
L'invention a pour but de procurer une composition répulsive pour insectes qui permet de remédier aux principaux inconvénients présentés par les compositions répulsives connues ; à savoir : odeur désagréable et durée d'efficacité limitée soit par absorption ou mé abolisa Li on de la composition par la peau, soit par la transpira ion due aux fortes chaleurs ou à des efforts ou encore par l'abrasion de la composition occasionnée notamment par le lavage de la surface traitée ou par le déplacement de l'air sur cette surface. C'est ainsi que l'on constate des diminutions d'efficacité de l'ordre de 60 %, par rapport à une atmosphère exempte de vent, lorsque le vent atteint une vitesse de 190m/minute . A cet effet, la composition suivant l'invention comprend au moins un agent répulsif actif, choisi parmi les extraits de pelargonium, géranium, lavande, pyrèthre, fleur de citronnier, ainsi que du N , N-dié hy1-m-toluamide , un agent plastifiant et un agent amplificateur de l'effet répulsif des susdits composés acLifs. Suivant une forme de réalisation de l'invention, l'agent plastifiant est un composé vinylique.The object of the invention is to provide an insect repellent composition which makes it possible to remedy the main drawbacks presented by known repellent compositions; namely: unpleasant odor and limited duration of effectiveness either by absorption or m abolishing Li on of the composition by the skin, or by perspiration due to high heat or stress or by abrasion of the composition caused in particular by washing the treated surface or by the movement of air on this surface. This is how we observe efficiency reductions of around 60%, compared to a wind-free atmosphere, when the wind reaches a speed of 190m / minute. To this end, the composition according to the invention comprises at least one active repellant, chosen from extracts of pelargonium, geranium, lavender, pyrethrum, lemon flower, as well as N, N-dié hy1-m-toluamide, a plasticizing agent and an agent amplifying the repellent effect of the above active compounds. According to one embodiment of the invention, the plasticizing agent is a vinyl compound.
Suivant une forme de réalisation avantageuse, le composé vinylique est de la polyvinylpyrrolidone. Suivant un mode de réalisation avantageux de l'invention, l'agent amplificateur est cyclopentane- l-one-2-npentane-3-methyl ethyl ester connu sous le nom d ' Hedione .According to an advantageous embodiment, the vinyl compound is polyvinylpyrrolidone. According to an advantageous embodiment of the invention, the amplifying agent is cyclopentane-1-one-2-npentane-3-methyl ethyl ester known under the name of Hedione.
Suivant un mode de réalisation particulièrement avantageux de l'invention, la composition comprend, en poids, de 30 à 75% d'éthanol à 95%, de 5 à 50% de N,N- diethyl-m-toluamide , de 0,là 2% de polyvinylpyrrolidone, de 2 à 10% de myristate d ' isopropyle, de 2 à 10% de dipropylène glycol, de 0,1 à 2,5% d'amplificateur, de 0,1 à 2,5% d'un agent d'homogénéisation solubilisant et d'extraits naturels de 0,1 à 2,5%.According to a particularly advantageous embodiment of the invention, the composition comprises, by weight, from 30 to 75% of 95% ethanol, from 5 to 50% of N, N-diethyl-m-toluamide, from 0, there 2% of polyvinylpyrrolidone, from 2 to 10% of isopropyl myristate, from 2 to 10% of dipropylene glycol, from 0.1 to 2.5% of amplifier, from 0.1 to 2.5% of a solubilizing homogenizing agent and natural extracts from 0.1 to 2.5%.
D'autres détails et particularités de l'invention ressortiront de la description donnée ci-après, à titre d'exemples non limitatifs, de compositions répulsives pour insectes suivant l'invention.Other details and particularities of the invention will emerge from the description given below, by way of nonlimiting examples, of insect repellant compositions according to the invention.
La composition suivant l'invention, qui est répulsive pour la plupart des insectes et notamment pour les moustiques suivants : Λedes Aegypti, Culex, Mansonia, Anophèles, Psorophora, pour les puces, les tiques, les taons, les mouches noires, les mouches d'étable, les Cerotopogonidae, a pour caractéristique principale de permettre la création, sur les surfaces couvertes et principalement sur la peau où les compositions répulsives perdent le plus rapidement leur efficacité à cause de l'absorption, la métabolisation , la transpiration et/ou l'abrasion, d'un film, qui résiste au temps, aux conditions extérieures ainsi qu'aux modifications de l'état de la surface couverte et qui régularise et freine sa libération des ingrédients actifs de la composition, dans lequel restent présents la majeure partie de ces ingrédients répulsifs actifs, ingrédients dont l'activité est avan ageusement accrue par l'incorporation dans la composition d'un amplificateur, ladite composition présentant en outre l'avantage d'être constituée en majeure partie de produits naturels non toxiques pour l'homme et les animaux .The composition according to the invention, which is repellent for most insects and in particular for the following mosquitoes: Λedes Aegypti, Culex, Mansonia, Anopheles, Psorophora, for fleas, ticks, horseflies, black flies, black flies stable, Cerotopogonidae, has the main characteristic of allowing the creation, on covered surfaces and mainly on the skin where the repellant compositions lose their effectiveness as quickly as possible due to absorption, metabolization, perspiration and / or l 'abrasion, a film, which resists time, external conditions as well as changes in the state of the covered surface and which regulates and slows its release from the active ingredients of the composition, in which most of these ingredients remain present active repellents, ingredients whose activity is advantageously increased by the incorporation into the composition of an enhancer, said composition also having the advantage of being made up mainly of natural products which are non-toxic for humans and animals .
Cette composition, dont l'odeur est agréable et qui contient, suivant l'invention et comme décrit ci- après, un agent plastifiant et fixant ainsi qu'un agent ampli icateur, a une réelle activité répulsive pendant une période minimale de 4 à 8 heures qui pourrait atteindre 14 heures suivant les conditions externes lorsqu'elle est appliquée dans les quantités suivantes, qui varient notamment suivant les conditions atmosphériques extérieures, telles que la température dont la hausse provoque la dispersion ou l'abrasion de 0,05 à 0,2 mg par cm sur la peau et deThis composition, whose odor is pleasant and which contains, according to the invention and as described below, a plasticizing and fixing agent as well as an amplifying agent, has real repulsive activity for a minimum period of 4 to 8 hours which could reach 14 hours depending on external conditions when it is applied in the following quantities, which vary in particular according to outdoor atmospheric conditions, such as the temperature whose rise causes dispersion or abrasion from 0.05 to 0, 2 mg per cm on the skin and
0,01 à 0,lmg/cmJ sur les cheveux ou les habits et sur le pelage des animaux.0.01 to 0.1 mg / cm J on hair or clothes and on the coats of animals.
Ladite composition, qui contient de la polyvinylpyrrolidone, qui constitue l'agent plastifiant et fixant pour la formation du film susdit, des extraits répulsifs actifs naturels, tels que pelargonium, géranium, lavande, pyrèthre, fleurs de citronnier, ainsi que du N-N-die hy1-m-toluamide , un amplificateur constitué par cyclopentane -l-one-2- npentane-3-methyl ethyl ester dont la propriété est d'assurer un effet de synergie avec les exraits répulsifs actifs, comprend avantageusement, en poids, de 30 à 75% d'éthanol à 95%, de 5 à 50% de N, N- 5 diéthyl-m-toluamide, de 0,4 à 2% de polyvinylpyrrolidone, de 2à 10% de myristate d ' isopropyle, de 2 à 10% de dipropylène glycol, de 0,1 à 2,5% de l'amplificateur susdit et de 0,1 à 2,5% d'un agent d'homogénéisation solubilisant, tel que duSaid composition, which contains polyvinylpyrrolidone, which constitutes the plasticizing and fixing agent for the formation of the abovementioned film, natural active repellent extracts, such as pelargonium, geranium, lavender, pyrethrum, lemon flowers, as well as NN-die hy1-m-toluamide, an amplifier consisting of cyclopentane -l-one-2- npentane-3-methyl ethyl ester whose property is to ensure a synergistic effect with the active repellent extracts, advantageously comprises, by weight, from 30 to 75% of 95% ethanol, from 5 to 50% of N, N-5 diethyl-m-toluamide, from 0.4 to 2% of polyvinylpyrrolidone, from 2 to 10% of isopropyl myristate, from 2 to 10% of dipropylene glycol, from 0.1 to 2.5% of the aforementioned enhancer and from 0.1 to 2.5% of a solubilizing homogenizing agent, such as
10 polyoxyéthylène nonyl phényl éther connu sous le nom de "Lamacite" et de 0,1 à 2,5% d'extraits naturels répulsifs. La composition susdite peut également comprendre un colorant améliorant son aspect, ce colorant, introduit dans la composition à raison de10 polyoxyethylene nonyl phenyl ether known as "Lamacite" and from 0.1 to 2.5% of natural repellents. The aforementioned composition may also comprise a dye improving its appearance, this dye, introduced into the composition at a rate of
•*_5 0,001% à 0,01% en poids, étant choisi parmi les colorants neutres par rapport aux constituants susdits . • * _5 0.001% to 0.01% by weight, being chosen from neutral dyes with respect to the above-mentioned constituents.
On a obtenu d'excellents résultats répulsifs des insectes, eten particulier des résultats durables,Excellent insect repellency results have been obtained, especially long-lasting results,
20 avec une composition comprenant, en poids, 65,5% d'éthanol à 95%, 20% de N, N-diéthyl-m-toluamide, 1% de polyvin lpyrrolidone, 8% de myristate d'isopropyle, 4% de dipropylène glycol, 0,1% d'agent amplificateur, 0,5% d'agent d'homogénéisation solubilisant et 0,9%20 with a composition comprising, by weight, 65.5% 95% ethanol, 20% N, N-diethyl-m-toluamide, 1% polyvinylpyrrolidone, 8% isopropyl myristate, 4% dipropylene glycol, 0.1% amplifying agent, 0.5% solubilizing homogenizing agent and 0.9%
25 d'extraits répulsifs naturels.25 natural repellents.
Suivant l'invention, la composition répulsive peut se présenter soit sous la forme d'un aérosol, soit sous la forme d'un gel pouvant être notamment utilisé dans un distributeur à tête de distribution àAccording to the invention, the repellant composition can be either in the form of an aerosol, or in the form of a gel which can in particular be used in a dispenser with a dispensing head.
30 bille (roll-on) ou encore sous forme de spray.30 ball (roll-on) or as a spray.
Quand elle se présente sous la forme d'un aérosol, on utilise comme gaz propulseur soit du durosol, à raison de 20 à 25% en poids, soit un mélange de propane et de butane à raison de 40% en poids .When it is in the form of an aerosol, either propellant is used as durosol, at a rate of 20 to 25% by weight, ie a mixture of propane and butane at a rate of 40% by weight.
Quand la composition se présente sous la forme d'un gel, elle comprend en poids, 45 à 55% de la composition définie ci-dessus, 25 à 35% d'eau déminéralisée, 12,7 à 17,5% d'alcool éthylique à 95%, de 0,1 à 1,3% d'un agent d'accroissement de la viscosité, tel qu'un polymère à très haut poids moléculaire connu sous le nom de "carbomère", de 1,5% à 4,5% d'huile de foie de morue hydrogénée, connu notamment sous le nom de "Cremophor 2H40" et de 0,5 à 2% de polyoxyéthylène (15) cocoamine connu sous le nom d ""Ethomeen C/25". On a obtenu une excellente composition, sous forme de gel stable, avec 49,5% de la composition définie ci-avant, 30% d'eau déminéralisée, 15,5% d'alcool éthylique à 95%, 1% de "Carbomère", 3% de "Cremophor 2H40" et 1% d"'Ethomeen C/25". Lorsque ce gel est destiné à être utilisé dans un distributeur à tête de distribution à bille (roll- on), on abaisse la viscosité du gel défini ci-dessus en augmentant la quantité de solvant.When the composition is in the form of a gel, it comprises by weight, 45 to 55% of the composition defined above, 25 to 35% of demineralized water, 12.7 to 17.5% of alcohol 95% ethyl, from 0.1 to 1.3% of a viscosity-increasing agent, such as a very high molecular weight polymer known as a "carbomer", from 1.5% to 4.5% of hydrogenated cod liver oil, known in particular under the name of "Cremophor 2H40" and from 0.5 to 2% of polyoxyethylene (15) cocoamine known under the name of "Ethomeen C / 25". An excellent composition was obtained, in the form of a stable gel, with 49.5% of the composition defined above, 30% of demineralized water, 15.5% of 95% ethyl alcohol, 1% of "Carbomer ", 3% of" Cremophor 2H40 "and 1% of" Ethomeen C / 25 ". When this gel is intended to be used in a dispenser with a roll-on dispensing head, the viscosity of the gel is lowered defined above by increasing the amount of solvent.
Lorsqu'elle est présentée en spray, la composition est avantageusement celle qui est définie ci-dessus, et plus particulièrement celle qui comprend 65,5% d'éthanol à 95%, 20% de N, N-diéthy1-m-toluamide , 1% de polyvinylpyrrolidone, 8% de myristate d ' isopropyle , 4% de dipropylène glycol, 0,1% d'amplificateur, 0,5% d'agent d'homogénéisation solubilisant et 0,9% d'extraits répulsifs naturels. When it is presented as a spray, the composition is advantageously that which is defined above, and more particularly that which comprises 65.5% of 95% ethanol, 20% of N, N-diethyl-1-m-toluamide, 1% polyvinylpyrrolidone, 8% isopropyl myristate, 4% dipropylene glycol, 0.1% amplifier, 0.5% solubilizing homogenizing agent and 0.9% natural repellents.

Claims

REVENDICATIONS : CLAIMS:
1 )Composition répulsive pour insectes destinée à être appliquée sur la peau humaine tout aussi bien que sur les cheveux et les vêtements, ainsi que sur le pelage des animaux, caractérisée en ce qu'elle comprend au moins un extrait répulsif actif, choisi parmi les extraits de pelargonium, géranium, lavande, pyrèthre, fleur de citronnier, ainsi que du N,N- Diethyl-M-Toluamide, un agent plastifiant et un agent amplifica eur de l'effet répulsif desdits composés actifs.1) insect repellant composition intended to be applied to human skin as well as to hair and clothing, as well as to the coat of animals, characterized in that it comprises at least one active repellent extract, chosen from extracts of pelargonium, geranium, lavender, pyrethrum, lemon flower, as well as N, N-Diethyl-M-Toluamide, a plasticizing agent and an agent amplifying the repellent effect of said active compounds.
2)Composition suivant la revendica ion 1, caractérisée en ce que l'agent plastifiant est un composé vinylique.2) Composition according to claim 1, characterized in that the plasticizing agent is a vinyl compound.
3)Composition suivant la revendication 2, caractérisée en ce que le composé vinylique est de la polyvinylpyrrolidone.3) Composition according to claim 2, characterized in that the vinyl compound is polyvinylpyrrolidone.
4)Composition suivant l'une quelconque des revendications 1 à 3, caractérisée en ce que l'agent amplificateur est du cyclopentane-l-one-2-npentane-3- methyl ethyl ester.4) Composition according to any one of claims 1 to 3, characterized in that the amplifying agent is cyclopentane-l-one-2-npentane-3-methyl ethyl ester.
5Composition suivant l'une ou l'autre des revendications 3 et 4, caractérisée en ce qu'elle comprend, en poids, de 30 à 75% d'éthanol à 95%, de 5 à 50% de N,N- diéthyl-m-toluamide, de 0,1 à 2% de polyvinylpyrrolidone, de 2 à 10% de myristate d ' isopropyle , de 2 à 10% de dipropylène glycol, de 0,1 à 2,5% d'amplificateur, et de 0,1 à 2,5% d'un agent d'homogénéisation solubilisant et de 0,1 à 2,5% d'extraits répulsifs naturels. 5 6Composition suivant la revendication 5, caractérisée en ce qu'on utilise, comme agent d'homogénéisation solubilisant, du polyoxyéthylène nonyl phényl éther.5Composition according to either of Claims 3 and 4, characterized in that it comprises, by weight, from 30 to 75% of 95% ethanol, from 5 to 50% of N, N- diethyl- m-toluamide, 0.1 to 2% polyvinylpyrrolidone, 2 to 10% myristate isopropyl, 2 to 10% dipropylene glycol, 0.1 to 2.5% enhancer, and 0.1 to 2.5% of a solubilizing homogenizing agent and 0.1 to 2.5% natural repellents. 5 6Composition according to claim 5, characterized in that one uses, as solubilizing homogenizing agent, polyoxyethylene nonyl phenyl ether.
7 Composition suivant l'une ou l'autre des 10 revendications 5 et 6, caractérisée en ce qu'elle comprend de 0,001% à00,l% en poids d'un colorant neutre par rapport aux constituantes précitées.7 Composition according to either of Claims 10 and 6, characterized in that it comprises from 0.001% to00.1% by weight of a neutral dye with respect to the above-mentioned constituents.
8 Composition suivant l'une quelconque des revendications 5 à 7, caractérisée en ce qu'elle8 Composition according to any one of claims 5 to 7, characterized in that it
X5 comprend, en poids, 65,5% d'éthanol à 95%, 20% de N,N- diéthyl-m-toluamide, 1% de polyvinylpyrrolidone, 8% de myristate d' isopropyle, 4% de dipro ylène glycol, 0,1% d'amplificateur et 0,5% d'agent d'homogénéisation solubilisant et 0,9% d'extraits répulsifs naturels.X5 comprises, by weight, 65.5% of 95% ethanol, 20% of N, N-diethyl-m-toluamide, 1% of polyvinylpyrrolidone, 8% of isopropyl myristate, 4% of dipro ylene glycol, 0.1% amplifier and 0.5% solubilizing homogenizing agent and 0.9% natural repellents.
20 9)Aérosol, caractérisé en ce qu'il comprend une composition suivant l'une quelconque des revendications 1 à 8 et un gaz propulseur.9) An aerosol, characterized in that it comprises a composition according to any one of claims 1 to 8 and a propellant gas.
10)Aérosol suivant la revendication 9, caractérisé en ce que le gaz propulseur est du10) Aerosol according to claim 9, characterized in that the propellant is
2 ' druosol, à raison de 20 à 25% en poids. ll)Aérosol suivant la revendication 9, caractérisé en ce que le gaz propulseur est un mélange de propane et de butane, à raison de 40% en poids.2 'druosol, at a rate of 20 to 25% by weight. ll) Aerosol according to claim 9, characterized in that the propellant gas is a mixture of propane and butane, in an amount of 40% by weight.
12)Gel, caractérisé en ce qu'il comprend une12) Gel, characterized in that it comprises a
30 composition suivant l'une quelconque des revendications 1 à 8, à raison de 45 à 55% en poids, 25 à 35% d'eau déminéralisée, 12,7 à 17,5% d'alcool éthylique à 95%, de 0,1 à 1,3% d'un agent d'accroissement de la viscosité, tel qu'un polymère à très haut poids moléculaire, de 1,5 à 4,5% d'huile de foie de morue hydrogénée et de 0,5% à 2% de polyoxyéthylène (15) cocoamine.30 composition according to any one of claims 1 to 8, in an amount of 45 to 55% by weight, 25 to 35% of demineralized water, 12.7 to 17.5% of alcohol 95% ethyl, 0.1 to 1.3% of a viscosity increasing agent, such as a very high molecular weight polymer, 1.5 to 4.5% liver oil of hydrogenated cod and from 0.5% to 2% of polyoxyethylene (15) cocoamine.
13)Gel suivant la revendication 12, caractérisé en ce qu'il comprend, en poids, 49,5% de la composition précitée, 30% d'eau déminéralisée, 15,5% d'alcool éthylique à 95%, 1% d'agent d'accroissement de la viscosité, 3% d'huile de foie de morue hydrogénée et 1% de polyoxyéthylène (15) cocoamine.13) Gel according to claim 12, characterized in that it comprises, by weight, 49.5% of the above-mentioned composition, 30% demineralized water, 15.5% 95% ethyl alcohol, 1% d viscosity enhancing agent, 3% hydrogenated cod liver oil and 1% polyoxyethylene (15) cocoamine.
14)Spray caractérisé en ce qu'il comprend une composition suivant l'une quelconque des revendications 1 à 8 . 14) Spray characterized in that it comprises a composition according to any one of claims 1 to 8.
PCT/EP1989/000062 1988-01-27 1989-01-20 Insect-repellent composition WO1989006904A1 (en)

Applications Claiming Priority (2)

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CH269/88-6 1988-01-27
CH26988A CH676412A5 (en) 1988-01-27 1988-01-27

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Cited By (14)

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Publication number Priority date Publication date Assignee Title
US5118711A (en) * 1990-09-27 1992-06-02 International Flavors & Fragrances Inc. Ketone, ketoesters and alcohol in repelling insects; use of aliphatic ester in attracting insects and process and apparatus for determination of insect repellency and attractancy
EP0495684A1 (en) * 1991-01-18 1992-07-22 Clilco, Ltd. Lice-repellant compositions
US5298250A (en) * 1990-08-06 1994-03-29 R & C Products Pty Ltd. Insect repellent
WO1995007024A1 (en) * 1993-09-11 1995-03-16 Anthony Pisacane Repellant material
US5411992A (en) * 1991-01-18 1995-05-02 Clilco Ltd. Lice repellant composition
EP0713647A1 (en) * 1994-11-24 1996-05-29 Jaico N.V. Insect-repellent composition based on pyrethrum extract
US5635174A (en) * 1992-09-18 1997-06-03 International Flavors & Fragrances Inc. Insect repellent and attractant compositions and methods for using same
US5683687A (en) * 1992-09-18 1997-11-04 International Flavors & Fragrances Inc. Insect attractant compositions and methods for using same
FR2755825A1 (en) * 1996-11-15 1998-05-22 Firmenich & Cie Cockroach repellent composition
WO1998023150A1 (en) * 1996-11-26 1998-06-04 Schering-Plough Healthcare Products Inc. Insect repellent emulsions
US6605643B1 (en) 1997-11-24 2003-08-12 Schering-Plough Healthcare Products, Inc. Insect repellent emulsions
WO2007093298A1 (en) * 2006-02-16 2007-08-23 Saltigo Gmbh Gel formulations for arthropod and plathelminth control
WO2007093297A2 (en) * 2006-02-16 2007-08-23 Saltigo Gmbh Water-in-oil formulation for arthropod and plathelminth control
WO2008090476A3 (en) * 2007-01-25 2008-10-30 Centre Nat Rech Scient Phytosanitary formulations

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GB9930104D0 (en) 1999-12-20 2000-02-09 Unilever Plc Aqueous hair styling compositions
DE102005015446A1 (en) * 2005-04-05 2006-10-12 Merck Patent Gmbh Synergists to enhance the effect of repellents

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EP0251464A2 (en) * 1986-05-27 1988-01-07 The Boots Company PLC Composition for the control of insects
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Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5298250A (en) * 1990-08-06 1994-03-29 R & C Products Pty Ltd. Insect repellent
US5118711A (en) * 1990-09-27 1992-06-02 International Flavors & Fragrances Inc. Ketone, ketoesters and alcohol in repelling insects; use of aliphatic ester in attracting insects and process and apparatus for determination of insect repellency and attractancy
EP0495684A1 (en) * 1991-01-18 1992-07-22 Clilco, Ltd. Lice-repellant compositions
US5411992A (en) * 1991-01-18 1995-05-02 Clilco Ltd. Lice repellant composition
US5635174A (en) * 1992-09-18 1997-06-03 International Flavors & Fragrances Inc. Insect repellent and attractant compositions and methods for using same
US5683687A (en) * 1992-09-18 1997-11-04 International Flavors & Fragrances Inc. Insect attractant compositions and methods for using same
WO1995007024A1 (en) * 1993-09-11 1995-03-16 Anthony Pisacane Repellant material
EP0713647A1 (en) * 1994-11-24 1996-05-29 Jaico N.V. Insect-repellent composition based on pyrethrum extract
FR2755825A1 (en) * 1996-11-15 1998-05-22 Firmenich & Cie Cockroach repellent composition
WO1998023150A1 (en) * 1996-11-26 1998-06-04 Schering-Plough Healthcare Products Inc. Insect repellent emulsions
US6605643B1 (en) 1997-11-24 2003-08-12 Schering-Plough Healthcare Products, Inc. Insect repellent emulsions
WO2007093298A1 (en) * 2006-02-16 2007-08-23 Saltigo Gmbh Gel formulations for arthropod and plathelminth control
WO2007093297A2 (en) * 2006-02-16 2007-08-23 Saltigo Gmbh Water-in-oil formulation for arthropod and plathelminth control
WO2007093297A3 (en) * 2006-02-16 2007-12-13 Saltigo Gmbh Water-in-oil formulation for arthropod and plathelminth control
WO2008090476A3 (en) * 2007-01-25 2008-10-30 Centre Nat Rech Scient Phytosanitary formulations
US8980793B2 (en) 2007-01-25 2015-03-17 Centre National De La Recherche Scientifique (Cnrs) Phytosanitary formulations

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CA1312006C (en) 1992-12-29
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